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Only four women have ever received the Nobel Prize in Physics. This episode features two of them! Andrea Ghez unlocked a secret of the universe when she figured out how to prove the existence of a super-massive black hole in the center of our galaxy.  Donna Strickland devised a way of producing far more intense and precise lasers. Those lasers have changed manufacturing, cancer treatments, and eye surgeries, and promise to offer insights into the fundamental principles of physics. Both Ghez and Strickland talk here about their lives and about becoming world-class scientists at a time when women were under-represented, under-appreciated, and often unrecognized for their achievements.