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An overview of work on probabilistic soft logic (PSL), an SRL framework for large-scale collective, probabilistic reasoning in relational domains and a description of recent work which integrates neural and symbolic (NeSy) reasoning. Our ability to collect, manipulate, analyze, and act on vast amounts of data is having a profound impact on all aspects of society. Much of this data is heterogeneous in nature and interlinked in a myriad of complex ways. From information integration to scientific discovery to computational social science, we need machine learning methods that are able to exploit both the inherent uncertainty and the innate structure in a domain. Statistical relational learning (SRL) is a subfield that builds on principles from probability theory and statistics to address uncertainty while incorporating tools from knowledge representation and logic to represent structure. In this talk, I’ll overview our work on probabilistic soft logic (PSL), an SRL framework for large-scale collective, probabilistic reasoning in relational domains. I’ll also describe recent work which integrates neural and symbolic (NeSy) reasoning. I’ll close by highlighting emerging opportunities (and challenges!) in realizing the effectiveness of data and structure for knowledge discovery. Bio: Lise Getoor is a Distinguished Professor in the Computer Science & Engineering Department at UC Santa Cruz, where she holds the Jack Baskin Endowed Chair in Computer Engineering. She is founding Director of the UC Santa Cruz Data Science Research Center and is a Fellow of ACM, AAAI, and IEEE. Her research areas include machine learning and reasoning under uncertainty and she has extensive experience with machine learning and probabilistic modeling methods for graph and network data. She has over 250 publications including 13 best paper awards. She has served as an elected board member of the International Machine Learning Society, on the Computing Research Association (CRA) Board, as Machine Learning Journal Action Editor, Associate Editor for the ACM Transactions of Knowledge Discovery from Data, JAIR Associate Editor, and on the AAAI Executive Council.. She is a Distinguished Alumna of the UC Santa Barbara Computer Science Department and received the UC Santa Cruz Women in Science & Engineering (WISE) award. She received her PhD from Stanford University in 2001, her MS from UC Berkeley, and her BS from UC Santa Barbara, and was a professor at the University of Maryland, College Park from 2001-2013. THE STRACHEY LECTURES ARE GENEROUSLY SUPPORTED BY OxFORD ASSET MANAGEMENT