ELI5 Laughing Gas - why is N20 called laughing gas?

What happens inside your brain when you inhale nitrous oxide? Why is it called laughing gas? When did we start using laughing gas for medical use cases? Is it safe?

... we explain like I'm five

Thank you to the r/explainlikeimfive community and in particular the following users whose questions and comments formed the basis of this discussion: linguista420, slugcunt69, infinitysquared and kodack10

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