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Featuring articles on alectinib in ALK-positive lung cancer, minimally invasive removal of cerebral hematomas, and CAR T-cell–mediated responses in recurrent glioblastoma; a review article on energy and macronutrients across the life span; a case report of a woman with falls and cognitive decline; a Medicine and Society on money as medicine; and Perspectives on back to the future in Alabama, on the end of B/Yamagata influenza transmission, and on the plight of DEI leaders.