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Starting in the fifteenth century, medical doctors from the Italian peninsula began accompanying Venetian consular missions to cities in the Mamluk and Ottoman empires. These doctors treated not only Venetian consular officials, but also local artisans and rulers. In this podcast, Valentina Pugliano discusses the experiences of these travelling doctors both in the Italian peninsula and in the Middle East. We explore their interactions with the local population and their effect on the medical ecology of the Middle East as well as the sources we use to write such histories. Together, the experiences of these doctors point to the connected histories of medicine and science in the early modern Mediterranean.