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Featuring articles on treatments for eosinophilic esophagitis, reteplase versus alteplase for acute ischemic stroke, dupilumab for COPD with type 2 inflammation, and brigatinib in NF2-related schwannomatosis; a review article on amyloidosis; a case report of a man with recurrent fever and liver lesions; and Perspectives on Alzheimer’s disease, biomarkers, and mAbs; on climate litigation for protecting public health; on carbon-footprint analyses in RCTs; and on the phantom of the organ.