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Dr. Leana Wen and Dr. Neil Skolnik discuss the up to the minute state of the COVID-19 pandemic, including the possibility of a fourth surge, the current vaccination status of the U.S. population, new CDC guidelines for fully vaccinated individuals, and an update on the pathophysiology, clinical manifestations, and clinical evaluation and treatment of COVID-19  Long Haulers Syndrome (Post Acute Sequelae of Covid-19).This segment was recorded on April 10, 2021 at the NACE Conversations in Primary Care 2021 live virtual broadcast, Episode 3.FacultyLeana S. Wen, MD, MScVisiting Professor, Health Policy and ManagementDistinguished Fellow, Fitzhugh Mullan Institute for Health Workforce EquityGeorge Washington University School of Public HealthWashington, DCNeil Skolnik, MDProfessor of Family and Community MedicineSidney Kimmel Medical CollegeThomas Jefferson UniversityPhiladelphia, PAThis podcast  is not accredited for CME credit.