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Practice Bulletin #95 - Published July 2008 (Reaffirmed 2017) 1. Normal physiologic changes in pregnancy that are relevant in anemia include increased blood volume, increased red blood cell mass, and increased iron stores. 2. Low serum ferritin is the most sensitive and specific single lab finding in iron deficiency anemia. 3. The CDC recommends universal screening for iron deficiency anemia in pregnancy along with universal supplementation. 4. B12 deficiency and folic acid deficiency are common causes of macrocytic anemia; folic acid deficiency much more likely than B12. 5. Blood transfusions are almost never indicated in pregnancy, apart from the rare case of a large, concealed placental abruption (Hgb l6 g/dL is associated with abnormal fetal oxygenation --g non-reassuring fetal heart rate patterns, reduced amniotic fluid volume, fetal cerebral vasodilation, and fetal death)Show Notes**Visit our friends at The Labor of Love Co. to send a pregnant person in your life a curated maternity or postpartum care package!** Wine pairing: 2018 Red Blend from Horse Heaven Hills Wine Growers Theme music by Evan Handyside Logo design by JD Dotson (jddotson1@gmail.com)