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Practice Bulletins #226 - Published October 2020 1. Cell-free DNA screening has the best sensitivity and specificity of all screening methods. But before you order it, it's best to get a prenatal ultrasound 2. Best non-cell-free screening modality is the sequential integrated serum screen (1st-tri serum + NT ultrasound + 2nd-tri serum) 3. Formal anatomy survey should be offered at 18 - 22 wga; can identify soft markers for T21 and T18 4.  Prenatal genetic screening should be offered to all pregnant women regardless of risk profile 5. Anything that doesn't add up, it's best to just refer to a genetics counselor or even your friendly MFM for clarification.Show Notes Wine pairing: 2017 Garnacha from Las Rocas Theme music by Evan Handyside Logo design by JD Dotson (jddotson1@gmail.com)