What Happens In A Caffeine Overdose

Max recommended amount of caffeine per day is 400mg.

@Chubbyemu case report video ► https://youtu.be/wj_AOzSSDMM 

Video version of this episode ► https://youtu.be/rn-WLpa_nyQ

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Music by  @Lifeformed 

Some caffeine is OK. 1-2 cups of coffee can generally be ok.  Unreasonably large amounts of caffeine NOT OK.  


References: 

[0] Hensher C, Vogel J. Insulin Euglycemic Therapy in the Treatment of Caffeine. Chest. 2020 May;157(5):e145-e149. https://pubmed.ncbi.nlm.nih.gov/32386647/  

[1] Multi-modal contributions to detoxification of acute pharmacotoxicity by a triglyceride micro-emulsion. J Control Release. 2015 Jan 28; 198: 62–70.  

[2] Rall TW, Sutherland EW. Formation of a Cyclic Adenine Ribonucleotide By Tissue Particles. J Biol Chem 1958, 232:1065-1076.  

[3] A Case of Exercise-Induced Rhabdomyolysis Associated With A Weight Loss Dietary Supplement. Military Medicine, 172, 6:656, 2007.  

[4] Yamada Y, et. al. The mode of action of caffeine on catecholamine release from perfused adrenal glands of cat. Br. J. Pharmacol. (1989), 98, 351-356.  

[5] Effects of Caffeine on Plasma Renin Activity, Catecholamines and Blood Pressure. N Engl J Med 1978; 298:181-186.  

[6] Caffeine resulting in severe rhabdomyolysis and acute renal failure. American Journal of Emergency Med 32 (2014) 111.e3-111.e4.  

[7] Eteng, MU, et. al. Recent advanced in caffeine and theobromine toxicities: a review. Plant Foods for Human Nutrition 51: 231-243, 1997.  

[8] Jabbar SB, et. al. Caffeine: A case report and review of literature. Am J Forensic Med Pathol. Vol 34, N4, Dec 2013.  

[9] Bioh G. et. al. Survival of caffeine. BMJ Case Rep 2013. bcr-2012-007454.

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