Tempus's Joel Dudley on Building a New Infrastructure for Precision Medicine

What if there were a single company that could connect hospital electronic health record systems to a massive genomic testing and analytics platform? It would be a little like Amazon Web Services (AWS) for healthcare—an enabling platform for anyone who wants to deploy precision medicine at scale. That's exactly what Joel Dudley says he's now helping to build at Tempus.

When Harry last spoke with Dudley in January 2019, he was a tenured professor of genetics and genomics at the Icahn School of Medicine at Mount Sinai Medical Center and director of the Institute for Next Generation Healthcare. But later that same year, Dudley was lured away to Tempus, founded in 2015 by Eric Lefkofsky, the billionaire co-founder of Groupon. 

Tempus is building an advanced genomic testing platform to document the specific gene variants present in patients with cancer (and soon other diseases) in order to match them up with the right drugs or clinical trials and help physicians make faster, better treatment decisions. In this week's show, Harry gets Dudley to say more about Tempus's business—and explain why it was an opportunity he couldn’t turn down.

You can find more details about this episode, as well as the entire run of MoneyBall Medicine's 50+ episodes, at https://glorikian.com/moneyball-medicine-podcast/

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TRANSCRIPT

Harry Glorikian: The last time I had Joel Dudley on the show in January 2019, he didn’t sound like a guy who was looking for a new job. At the time, he was a professor of genetics and genomics at the Icahn School of Medicine at Mount Sinai, and the director of the Institute for Next Generation Healthcare. He was publishing breakthrough papers on the use of advanced statistics to find unexpected biomarkers for diseases like Alzheimer’s.  And he had a long to-do list of ways he wanted to push his fellow physicians to become more data-driven.

But lo and behold, later in 2019 Dudley was lured away from Mount Sinai by Eric Lefkofsky, the billionaire co-founder of Groupon. Lefkosky had started a new company called Tempus, with the goal of creating an advanced genomic testing platform to help oncologists and other physicians make faster, better treatment decisions for their patients. 

Lefkofsky showed Dudley what the company was doing to document the specific gene variants present in each cancer patient, in order to match the

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